<<返回上一页

Cystitis drug conscripted in war on CJD

发布时间:2019-03-08 10:10:02来源:未知点击:

By Michael Day A DRUG used to treat cystitis may protect surgeons who accidentally expose themselves to infection by Creutzfeldt-Jakob disease. Moira Bruce and her colleagues at the Institute for Animal Health in Edinburgh found that the drug, called pentosan polysulphate, increased the incubation period of scrapie, a related disease. Seven hours after mice were given a fatal dose of scrapie-infected brain tissue, they were injected with 1 milligram of the drug. In one mouse strain, this increased the incubation period by 65 per cent. In another two strains, it protected the animals completely (The Lancet, vol 353, p 117). Bruce says the drug may offer protection to neurosurgeons who cut themselves while operating on patients who have CJD. “But the key is knowing when infection occurs and acting quickly,” she says. Bruce believes the drug is unlikely to have much effect once symptoms start to show. However,